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A newly published review of research on marijuana and chronic nerve pain concludes that treatment with cannabinoids offers “significant relief from chronic pain” with “minimal to no side effects”—potentially providing patients a “life-changing alternative” to conventional pharmaceuticals.

“The positive effects of cannabinoids in pain management are clear and their merit in the treatment thereof is evident,” says the research, published last month in the journal Cureus. It adds that “the fact that cannabinoids are natural garners it support over traditional synthetic and semi-synthetic drugs.” “Compared to placebo, cannabinoids provided significant relief from chronic pain (33% vs 15%) as measured by the visual analog scale,” the paper says. “The transdermal application of CBD led to a more pronounced reduction in sharp pain, according to the neuropathic pain scale. Minimal to no side effects were recorded, further highlighting the potential benefits of cannabinoids.”

“Cannabis-derived drugs in their most effective formulation and dosage can be a major breakthrough in the treatment of chronic pain,” authors continue. “It is thus obvious that a greater emphasis should be put on medical cannabis as a treatment option through larger scale clinical trials.” As more states have legalized medical marijuana, pain has been a top qualifying condition in most jurisdictions. That’s backed up by reports from patients and health care providers indicating that cannabis is an effective tool for pain management.

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